Certified Wound Care Nurse (CWCN) Practice Exam

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Prepare for the Certified Wound Care Nurse Exam. Study with flashcards, multiple choice questions, and get hints and explanations. Ensure success in your certification!

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Which of the following antimicrobial products is safe for use with collagenase?

Crystal violet
Hydrogen peroxide
Saline
Betadine

The correct answer is: Crystal violet

Collagenase is a proteolytic enzyme designed to facilitate the breakdown of collagen in necrotic or devitalized tissue, promoting wound healing. The correct choice in this context is a product that does not interfere with the activity of collagenase and can be safely used in conjunction with it. Crystal violet, known for its antimicrobial properties, is compatible with collagenase because it does not affect the enzyme’s action or inhibit its ability to effectively assist in debridement. This makes it a safe option for use around collagenase treatment. Other products mentioned, while having their own properties, can have detrimental effects when used with collagenase. Hydrogen peroxide can cause cytotoxic effects and may inactivate proteolytic enzymes, including collagenase. Saline is generally considered safe, but it does not possess antimicrobial properties, which limits its effectiveness in controlling infection. Betadine, an antiseptic solution, contains iodine that can interfere with the enzymatic activity of collagenase, potentially hampering healing efforts. Thus, the efficacy of the chosen antimicrobial product in conjunction with collagenase treatment is critical for promoting optimal wound healing outcomes.